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・ Leukotriene B4
・ Leukotriene B4 receptor
・ Leukotriene B4 receptor 1
・ Leukotriene B4 receptor 2
・ Leukotriene C4
・ Leukotriene C4 synthase
・ Leukotriene C4 synthase deficiency
・ Leukotriene D4
・ Leukotriene E4
・ Leukotriene receptor
・ Leukotriene receptor antagonist-associated Churg–Strauss syndrome
・ Leukotriene-A4 hydrolase
・ Leukotriene-B4 20-monooxygenase
・ Leukotriene-C4 hydrolase
・ Leukotriene-C4 synthase
Leukotriene-E4 20-monooxygenase
・ Leul Abate
・ Leulinghem
・ Leulinghen-Bernes
・ Leulumoega
・ Leum Uilleim
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Leukotriene-E4 20-monooxygenase : ウィキペディア英語版
Leukotriene-E4 20-monooxygenase

In enzymology, a leukotriene-E4 20-monooxygenase () is an enzyme that catalyzes the chemical reaction
:(7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14- tetraenoate + NADPH + H+ + O2 \rightleftharpoons 20-hydroxyleukotriene E4 + NADP+ + H2O
The 5 substrates of this enzyme are (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-, tetraenoate, NADPH, H+, and O2, whereas its 3 products are 20-hydroxyleukotriene E4, NADP+, and H2O.
This enzyme belongs to the family of oxidoreductases, specifically those acting on paired donors, with O2 as oxidant and incorporation or reduction of oxygen. The oxygen incorporated need not be derived from O2 with NADH or NADPH as one donor, and incorporation of one atom o oxygen into the other donor. The systematic name of this enzyme class is (7E,9E,11Z,14Z)-(5S,6R)-6-(cystein-S-yl)-5-hydroxyicosa-7,9,11,14-te traenoate,NADPH:oxygen oxidoreductase (20-hydroxylating). This enzyme is also called leukotriene-E4 omega-hydroxylase. This enzyme participates in arachidonic acid metabolism.
==References==

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